hepatocellular injury

Investigation on Double Direction Regulating and Controlling of Tissue Transglutaminase in Hepatocellular Injury and Proliferation

组织转谷氨酰胺酶在肝细胞损伤和增生中的双向调控机制的研究

Conclusions Heavy alcohol intake is a risk factor of As , and its mechanisms is related to the lipid metabolic disturbance caused by chronic hepatocellular injury .

结论酗酒是汉人As的危险因子，其机制与慢性肝细胞损伤致脂质代谢紊乱有关。

Mechanism of acetaminophen - induced hepatocellular injury

扑热息痛引起肝细胞损害的机制

Protective effect of taurine and branched chain amino acid on lipid peroxidation in cultured hepatocellular injury in rats

牛磺酸和支链氨基酸对大鼠肝细胞氧化损伤的保护作用

It suggests the protection , which is associated with anti-lipid peroxidation , of GPS on CCl_4 induced hepatocellular injury in vitro .

提示GPS能减轻CCL4能减轻CCl4对离体培养的大鼠肝细胞损伤，保护肝细胞DNA合成，其作用机理与抗脂质过氧化有关。

Objective To study whether the melatonin ( MT ) can attenuate hepatocellular injury caused by ischemia-reperfusion ( I / R ) injury in rat liver .

目的利用大鼠肝脏热缺血再灌注（I/R）损伤模型，研究褪黑素（MT）对再灌注损伤肝脏的保护作用。

Conclusion Taurine and branched chain amino acid can protect the hepatocytes injured by CCl 4 . The possible mechanism is the prevention of lipid peroxidation in cultured hepatocellular injury .

结论牛磺酸和支链氨基酸对CCl4所致的肝细胞损伤具有保护功能，其保护作用可能是通过抗脂质过氧化作用实现的。

The HBV replication cycle is not directly cytotoxic to hepatocytes . It is now thought that host immune responses to viral antigens displayed on infected hepatocytes are the principal determinants of hepatocellular injury .

HBV的复制并不会直接对肝细胞造成损害，现在认为在感染的肝细胞中，宿主的免疫系统对病毒抗原的反应是肝损害的决定因素，机理不完全清楚。

Than in healthy controls . The results indicate that NK activity , CD8 + T-cell subset and CD4 / CD8 ratio in patients with acute hepatitis C were relationship with the hepatocellular injury in patients with acute hepatitis C.

CD8~+T细胞亚群百分比的增加，可能与急性丙型肝炎患者的肝细胞损伤及发病机制有关。

The substances resulted from inflammation , like reactive oxygen species and NO , cause hepatocellular injury and gene mutation . Consequently , tumor cells are formed . IFN - γ is a multifunctional cytokine , which plays an important part in the immune response of anti-infection and anti-tumor .

炎症反应过程中产生的活性氧、NO等能够损伤肝细胞引起细胞发生基因突变形成肿瘤细胞IFN-γ是一种多功能细胞因子，在机体的抗感染、抗肿瘤免疫反应中发挥重要作用。

To study the relationship between hepatocellular injury in hepatitis B patient and hepatocyte stimulator substance , HSS )、 interleukin-8 ( IL-8 ), enzyme linked immunohistochemical assay ( ELISA ) was performed in 177 patients with hepatitis B to determine the serum levels of IL-8 and HSS .

为研究乙肝患者的肝细胞损害与白细胞介素8（IL－8）及肝细胞刺激物质（HSS）的关系，本文应用ELISA法检测177例乙肝患者血清的IL－8和HSS含量。

Hepatocellular injury during hepatitis B virus ( HBV ) infection is postulated ^ to result from an human leucocyte antigen ( HLA ) restricted T-cell host immune response against HBV antigens . However , it is not known if HBV itself can induce HLA expression on infected hepatocytes .

乙型肝炎病毒（HBV）所致的肝细胞坏死，被认为是与人类白细胞抗原（HLA）有关的MHC限制的T细胞为主的免疫应答的结果。

Conclusion : CD 54 was strongly expressed in HCC , but this could not evoke effective anti tumor immune response and / or induce hepatocellular immune injury . This may be related to the lower expression rate of HLA ABC .

结论：CD54在HCC组织中高度表达并不能引起有效抗肿瘤免疫应答和肝细胞免疫损伤，这可能与HLA-ABC表达率较低有关。

CONCLUSION The hepatocellular immune injury and effective anti-tumor immune response might be induced by sufficient expression of CD54 , CD80 , CD86 and HLA-ABC concurrently , and absence or poor expression of CD80 and CD86 might be the main reason for immune escape of hepatocarcinoma .

结论CD54，CD80，CD86和HLA-ABC在LC和HCA3中的同时足量表达有可能引起肝细胞损伤和有效抗肿瘤免疫应答，而CD80，CD86表达的缺失或不足可能是HCC产生免疫逃避的主要原因。